
Jeremy Airey, senior professional development leader at the National Science Learning Centre
Hot topic of the moment is Craig Venter’s announcement that his group has created a synthetic life form (dubbed Synthia by the media). This attention-grabber raises interesting discussion points for biology classrooms.
Amongst these is the meaning of “synthetic”. It certainly is not true that Venter’s group has “created life”. The functions of too many biological tools were required to make that claim – not least within the cells that received the new genome. However, it is a technical tour de force: to construct a new genome according to information on a computer, transplant it into a prepared cell, and to persuade that cell to “boot up” the genome. It’s also an important proof of concept for synthetic biology.
Why are biologists so excited? Synthetic biology is a burgeoning discipline, with practical applications projected to include clean biofuels, new polymers and cheaper medicines. Most synthetic biology is focused on less ambitious strategies than Venter’s. But, as he did with human genome sequencing, Venter has really upped the stakes, raising the prospects for much faster progress.
There are philosophical issues aside from the practical aspects. For me, though vitalism has no place in my understanding of life, Synthia is a sharp reminder that it’s all nuts and bolts. I doubt I am the only one who’s slightly disappointed. I need to get over my romantic side, recall that there are plenty of mysteries still to solve, and remember that for a scientist, understanding how something works does not diminish its wonder. Is that what our learners think?

Related courses
The Bringing Cutting Edge Science into the Classroom: Genetics course at the regional Science Learning Centres will provide you with the opportunity to keep up to date with latest developments in the field of biology, and use a variety of activities and approaches to integrate contemporary genetics into your teaching.
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Jeremy Airey, senior professional development leader at the National Science Learning Centre.
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